Stepping into Casa Santiago Botero is not merely arriving at a destination; it is an invitation to inhabit a masterpiece. Nestled within the storied 18th-century walls of Cartagena’s Old City, this boutique museum-villa breathes with the rhythm of Colombian heritage. The property transcends the traditional hotel experience, offering a sanctuary where guests live amongst the brushstrokes of masters like Fernando Botero, Ana Mercedes Hoyos, and David Manzur.
Under the artistic direction of owner and artist Manuela Echeverri, the villa has been restored to preserve its colonial soul while embracing a bold, modern aesthetic. Here, one doesn't simply stay; one enters a living canvas where tropical gardens meet high-vaulted ceilings and iron chandeliers illuminate the bridge between history and high design.
Life at the Casa is a sensory process of discovery. From the morning ritual of a chef-prepared breakfast in the lush courtyard to a sunset cocktail on the panoramic rooftop terrace, every moment is designed with artistic intent. It is a place of quiet grandeur and vibrant color—a private oasis where the luxury of silence is punctuated only by the soft splash of the pool and the rustle of native palms. Because in Cartagena, many seek a place to sleep, but at Casa Santiago Botero, guests wake up inside a work of art. You can read more about this property in Condé Nast Traveler.
City Area 
Authentic Design 
Historic Charm 
Exclusive Products 
Prime Location 
Rare Stay 
Restored Place 
Museum Hotel The property is a classic example of 18th-century Spanish Colonial architecture, meticulously restored with a Contemporary Fusion interior. Characterised by its original coral stone walls, double-height "puntal alto" ceilings with exposed wooden beams, and a central open-air courtyard that promotes natural ventilation. The design integrates modern luxury through a private elevator, an iron-accented "Great Room," and a seamless flow between indoor and outdoor tropical spaces.
Cartagena de Indias, Colombia
This option offers an intimate retreat featuring a King or Queen bed, air conditioning, and a luxury private bathroom. The room stands out for its refined colonial design, views of the internal gardens or the pool, and boutique hotel services such as included breakfast, high-speed Wi-Fi, and 24-hour personalized attention.
Cartagena de Indias, Colombia
The entire property accommodates up to 15 guests across 5 spacious bedrooms. It is an architectural gem featuring an elevator, a private pool surrounded by tropical greenery, and a spectacular rooftop terrace with a pizza oven and BBQ. The rental includes a full-time staff (chef, butler, and housekeeping) for a worry-free experience, along with climate-controlled social areas and an on-site private spa.
